Amlodipine

  Amlodipine:-
          It is a channel antagonist of the dihydropyridine group. Iy inhibits the transmembrane influx of calcium ion into cardiac & decrease blood pressure. It has also coronary effect resulting in decreased frequency & severty of attaks of angina. It has slow onset of action & long duration of action.
Dose:-
     Adult: hypertention: 5mg od,              increase 10mg od          
     Angina: 5-10mg

  

Calcium

Calcium:

      It is essential for the functioning of cells. More then 90% of calcium in the body is preserved in the skeletal structure. 700mg of calcium is turnover daily of the minerals in bone, as the bone is continuously remodeled.

Sources of calcium:-

      Milk, dairy product.

Daily requirement:-

      Adult: 800mg/day

      Pregnancy and lactation: 1200mg/day

Paracetamol/Acetaminophen

       It is synthetic non-opiate derivatives of para-aminophenol which produces analgesia and antipyresia and it has no/weak anti inflammatory activity. Unlike salisylates it does not have uricosuric activity. Paracetamol produces analgesic action by elevation of the pain threshold & antipyretic through action on the hypothalamic heat regulating centre.

Indication:

• Pyrexia (fever)
• Mild to moderate pain
• Toothache, bodyache
• After minor surgery (to reduce the pain)
• Musculoskeletal disorder
• Post vaccination pain & fever of children
• This makes it a particularly useful alternative for people who suffer from peptic ulcer or who can not tolerance Aspirin.

Dose:
      Adult: 500mg-1000mg tid/qid sos
      Child: less than 3 months: 10mg/kg;above 3 months;1o-15mg/dose(3-4doses